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Hair loss · Treatments compared

Hair loss treatments compared

Medicine, laser and micrografts

What each option for pattern hair loss does, what the trials show, and why the cause is found first.

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Assessed and planned by Dr Sin Yong, Medical Director · MBBS (NUS) · MRCS (Edinburgh) · MSc Aesthetic Medicine (London) · MSc Practical Dermatology (Cardiff) · Professional Diploma in Obstetrics & Gynaecology (RCPI) · Designated DEKA Centre of Excellence
In short · Doctor’s answer

Pattern hair loss is treated with medicines that address the hormonal driver, low-level laser therapy, fractional laser to the scalp and scalp micrografts, usually in combination. Medicines have the strongest trial evidence; laser and micrografts add to them. No treatment regrows follicles that are permanently lost, so the cause is found first. See hair loss treatment in Singapore.

Written by Dr Sin Yong, Medical Director, IN Eternity Clinic · MSc Practical Dermatology (Cardiff) · Studies checked against PubMed ·
At a glance

The main options side by side

A general comparison for pattern (androgenetic) hair loss. Plans are set after assessment.
OptionSuitsHow it worksEvidenceDowntime
Oral and topical medicinesMen and women with pattern lossSlow the hormonal driver or lengthen the growth phaseStrongest; many randomised trialsPrescribed and monitored by a doctor
Low-level laser (H2LT)Early thinning; alongside medicineLight energy to stimulate folliclesModerate; 9 of 11 studies positiveNo downtime
Fractional laser (1540 nm)Diffuse thinningTiny heat columns in the scalp to prompt growthSmall studiesMild redness
Scalp micrografts (Regenera Activa)Thinning areasYour own scalp tissue processed and injectedSmall studiesSmall scabs about a week
Evidence

What the trials show

What the research says
  • A meta-analysis found low-level laser therapy, 5% and 2% minoxidil and 1 mg finasteride in men, and 2% minoxidil in women all superior to placebo (J Am Acad Dermatol 2017).
  • A network meta-analysis in men found the largest gain in hair count at 24 weeks with 0.5 mg dutasteride, 7.1 hairs/cm² more than 1 mg finasteride (JAMA Dermatol 2022).
  • A review of 11 low-level laser studies (680 people) found significant gains in hair count or density in 9 of 11 (Lasers Surg Med 2017).
  • In 27 women given a 1550 nm fractional laser for five months, hair density rose from 100 to 157 per cm² and thickness from 58 to 75 µm (J Eur Acad Dermatol Venereol 2011). IN Eternity uses a 1540 nm laser of the same class.
  • In a multicentre study of autologous scalp micrografts, hair density rose by about 28 hairs/cm² in women and 30 hairs/cm² in men at 12 months (Aesthetic Plast Surg 2025).
Choosing

How the options are combined

Most plans start with medicine for the hormonal driver, because it has the strongest evidence, and add in-clinic treatment to build density. Shedding after illness, stress or childbirth (telogen effluvium) is handled differently: the trigger is found and corrected, and blood tests check iron, vitamin D and thyroid. Scarring alopecia is referred for dermatology care.

  • Change is judged at three, six and twelve months with standardised photographs.
  • Stopping medicine usually lets pattern loss resume over months.
  • Results vary; no option promises a set amount of regrowth.

See also oral vs topical minoxidil and hair loss treatment cost.

Questions

Hair loss treatments: questions

Which hair loss treatment works?

Medicines have the strongest evidence for pattern hair loss, and low-level laser also beat placebo in a meta-analysis. Fractional laser and micrografts have smaller studies and are usually added to medicine. The right mix depends on the cause.

Is laser treatment for hair loss effective?

A review of 11 studies found significant gains in hair count or density in 9 of them. Laser suits early thinning and alongside medicine.

How long before hair loss treatment shows results?

Hair cycles are slow; most people judge change at three to six months, with a fuller picture at twelve months.

Can hair loss treatment regrow a bald area?

Treatment can thicken thinning hair, but follicles that are permanently lost do not regrow. Earlier treatment keeps more hair.

Is postpartum hair loss treated the same way?

No. Shedding after childbirth is usually temporary telogen effluvium; checks for iron and thyroid problems come first, and pattern-loss treatment is only added if needed.

References

  1. Adil A, Godwin M. The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis. J Am Acad Dermatol 2017;77(1):136-141.e5. doi:10.1016/j.jaad.2017.02.054
  2. Gupta AK, Venkataraman M, Talukder M, et al. Relative Efficacy of Minoxidil and the 5-α Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis. JAMA Dermatol 2022;158(3):266-274. doi:10.1001/jamadermatol.2021.5743
  3. Afifi L, Maranda EL, Zarei M, et al. Low-level laser therapy as a treatment for androgenetic alopecia. Lasers Surg Med 2017;49(1):27-39. doi:10.1002/lsm.22512
  4. Lee GY, Lee SJ, Kim WS. The effect of a 1550 nm fractional erbium-glass laser in female pattern hair loss. J Eur Acad Dermatol Venereol 2011;25(12):1450-4. doi:10.1111/j.1468-3083.2011.04183.x
  5. Gentile P, Garcovich S, Perego F, et al. Autologous Micrografts Containing Nanovesicles, Exosomes, and Follicle Stem Cells in Androgenetic Alopecia: In Vitro and In Vivo Analysis Through a Multicentric, Observational, Evaluator-Blinded Study. Aesthetic Plast Surg 2025;49(1):43-58. doi:10.1007/s00266-024-04439-7

Book an assessment

IN Eternity Clinic, 9 Scotts Road, #12-01 Pacific Plaza, Singapore 228210. By appointment with Medical Director Dr Sin Yong. Monday to Saturday, 11am to 8pm. WhatsApp or call +65 8815 3008. The consultation fee is waived with any medical treatment.

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