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Cost Guide · Rejuran · Polynucleotides · Orchard Road

Rejuran Price in Singapore: What You Are Paying For

Variant, volume and visits decide the figure.

Rejuran is a polynucleotide injectable priced by the product used and the course planned. At IN Eternity Clinic on Orchard Road, Dr Sin Yong assesses your skin first, then gives you a written quote that shows each part.

WhatsApp to Enquire →Key facts ↓
PN
Polynucleotide injectable
Course
Usually several sessions
Written
Quote after assessment
Genuine
Registered product only
Assessed and treated by Dr Sin Yong, Medical Director · MBBS (NUS) · MRCS (Edinburgh) · MSc Aesthetic Medicine (London) · MSc Practical Dermatology (Cardiff) · Designated DEKA Centre of Excellence

Rejuran price in Singapore depends on which variant is used, how many syringes your skin and areas need, how many sessions the course runs to and how the product is delivered. Genuine, registered product and doctor time are fixed costs. At IN Eternity Clinic, Dr Sin Yong gives a written, itemised quote after assessing your skin.

Key facts
  • What it is: purified polynucleotide (PN) chains derived from salmon DNA, injected into the dermis as a skin-quality treatment rather than a volumiser.
  • Proposed mechanism: polynucleotides and related PDRN act partly through adenosine A2A receptors, supporting tissue repair, fibroblast activity and a calmer inflammatory response.
  • Variants: Rejuran Healer is the general skin-quality product; other formulations exist for thin under-eye skin and for acne scars, at different concentrations.
  • Volume: product comes in single-use syringes; the number needed depends on the areas treated and skin thickness.
  • Course: benefit builds over a course of sessions spaced a few weeks apart, so the session count is a large part of the total.
  • Delivery: micro-injections by the doctor place product evenly in the dermis; needle-free assisted delivery is a different technique with different consumables.
  • Sourcing: genuine product registered with the Health Sciences Authority, from an authorised supplier, is a fixed cost that cannot be cut without cutting corners.
  • The quote: at IN Eternity Clinic the variant, syringe count, sessions and review are written into an itemised quote before the first session.
Reviewed by Dr Sin Yong, Medical Director, IN Eternity Clinic · Last updated
Why prices differ

Why does Rejuran price vary so much between clinics?

Rejuran is often advertised as if it were a single treatment with a single price, but what is actually injected varies. Different formulations are made for general skin quality, for the thin skin under the eyes and for acne scars. The amount used depends on how many areas are treated and on how thin or damaged the skin is. And because benefit builds over a course rather than after one visit, the number of sessions often matters more to the total than the price of any single session.

The way the product reaches the skin also differs. Some clinics inject it in a closely spaced grid of micro-injections; some use assisted delivery methods; and some sell “Rejuran facials” that apply a topical cosmetic product with no injection at all. These are not the same treatment, and comparing their prices directly tells you very little.

Patient discussing a written Rejuran plan with the doctor
Illustrative image. Not a patient of IN Eternity Clinic.
The cost drivers

What drives the price of Rejuran?

Six factors account for most of the difference between quotes.

FactorWhat changesWhy it affects cost
VariantGeneral, under-eye or scar formulationDifferent products, concentrations and uses
SyringesHow much product per sessionEach single-use syringe is a fixed cost
SessionsLength of the courseBenefit builds over several visits
DeliveryMicro-injection or assisted deliveryDifferent time and consumables
AreasFace, under-eye, neckEach area adds product and time
ReviewChecks between sessionsLets the plan change before the next visit

Variant. Rejuran Healer is the formulation used for general skin quality: texture, fine lines, dullness and resilience. Other formulations exist for the delicate under-eye skin (Rejuran i) and for atrophic acne scars (Rejuran S). They are priced differently and are not interchangeable; using a scar product across the whole face, or a general product in a deep scar, wastes money. If a different variant would suit your skin, Dr Sin Yong will explain whether he would use it and why.

Syringes and areas. Product comes in single-use syringes that cannot be kept for a later visit once opened. A full face may need more than one; adding the neck or under-eyes needs more again. Thin, sun-damaged skin may need product spread over more points, which takes more time as well as more product.

Sessions. Rejuran is usually planned as a course of several sessions a few weeks apart, then reviewed. The course length is set by how your skin responds, which is why a fair quote states the planned number but leaves room to stop or change direction at review.

“The price of Rejuran is mostly the product and the course. The part I will not cut short is checking that it is the right product for your skin.”
— Dr Sin Yong, Medical Director, IN Eternity Clinic
Delivery and comfort

Does the delivery method change the price?

Yes. Placing many small deposits evenly in the dermis with a fine needle is slow, careful work, and the doctor’s time is part of the cost. Numbing cream is applied for twenty minutes or more beforehand, and small bumps are visible for a day or so afterwards. A small comparative study found that needle-free jet delivery of polynucleotide was also effective, with a different comfort and recovery profile. At IN Eternity Clinic, a needle-free option is available through the Deep Synergy Booster, and Dr Sin Yong will explain which route suits your skin and timetable.

What does not count as a Rejuran injection treatment is a facial that applies a polynucleotide-containing skincare product to the surface. Large molecules applied to intact skin do not reach the dermis in the same way. Such facials may feel pleasant, but they should be priced, and judged, as facials.

Sealed product box with blank label on stone
Illustrative image. Not a patient of IN Eternity Clinic.
Who it suits

Who gets value from Rejuran, and what does it cost over a year?

Rejuran tends to give the most value where the skin itself is the problem: thinning, dullness, fine crepe, enlarged pores, sensitivity after sun exposure or a weakened barrier, and early acne scarring. People in their thirties and forties who want firmer, more resilient skin without any change in shape are typical candidates. It is also used where skin needs support to recover, for example between laser sessions, under medical guidance.

It gives less value where the problem lies deeper. Lost volume, hollows, jowls and heavy laxity are not treated by polynucleotides, and pigment such as melasma needs a different plan. Paying for a long course in those situations is paying for the wrong layer. For skin that is mainly dry rather than thin, a hyaluronic acid booster may be more economical. Dr Sin Yong will say if a different treatment would use your budget better.

The first course is the largest outlay because it is several sessions close together. After review, many people move to occasional maintenance spaced months apart rather than repeating the full course. How often depends on age, skin condition, sun exposure and what else is being done. A plan that sets maintenance by your response, rather than by a calendar sold in advance, usually costs less over time and is easier to stop if the benefit is not worth it to you. If you are combining Rejuran with laser or energy treatments, ask for the combined plan over the year so you can see the total and the order, not only the price of each part on the day.

A fair quote

What should a fair Rejuran quote include?

A fair quote names the product and variant, states how many syringes will be used per session and in which areas, gives the planned number of sessions and the spacing between them, and says who will inject. It should list numbing, aftercare and whether review visits are included. If the quote is for a course, it should say what happens if you stop part way, or if the doctor recommends changing the plan at review.

You are also entitled to see the product. Genuine Rejuran comes sealed, with batch information on the pack. At IN Eternity Clinic product is opened in front of you, and you can read more about how the clinic sources injectables on the product sourcing page and how registration works on HSA registration explained. If you are told a product is “the same as” Rejuran but cheaper, ask for its name and registration status; similar-sounding polynucleotide products are not interchangeable.

Red flags

Red flags when comparing Rejuran prices

A price below what genuine product could cost. Unregistered imports, unknown “salmon DNA” injectables and product split between patients all exist. A very low price is worth a question about where the product came from. A long prepaid course sold on the day. A course can be planned in advance, but committing to many sessions before your skin has responded to the first is a sales decision.

No named injector, or injection by a non-doctor. Rejuran is an injectable medical product. Vague volume. “Full face Rejuran” without a syringe count cannot be compared with anything. Promises of a fixed result. Response varies with age, skin condition and sun exposure. More signs to watch for are in aesthetic clinic red flags.

At IN Eternity Clinic

How Rejuran is quoted at IN Eternity Clinic

Dr Sin Yong first checks whether a polynucleotide is the right tool. For skin that mainly needs hydration, a hyaluronic acid booster such as Profhilo may suit better; for laxity, an energy-based treatment may be more useful; for pigment, neither helps much. If Rejuran is suitable, he decides the variant, the number of syringes, the areas and the spacing of sessions.

You then receive a written, itemised quote with each of those parts stated, including numbing, aftercare and review. Nothing is added on the day without your agreement, and the course is reviewed as it goes rather than fixed in advance. For a side-by-side view of the main options, read Rejuran vs Profhilo vs Juvelook.

Myths and facts

Common myths, answered

Questions

Frequently asked questions

How much does Rejuran cost in Singapore?

It depends on the variant, the number of syringes per session, the areas treated and the number of sessions in the course. A single under-eye session and a full-face course with the neck are very different treatments. At IN Eternity Clinic, Dr Sin Yong assesses your skin and gives you a written quote that itemises each of these before you commit.

What is the Rejuran Healer price based on?

Mainly on the number of syringes used and the number of sessions planned, plus the doctor’s time and aftercare. Rejuran Healer is the general skin-quality formulation; its cost per session depends on how many areas are treated and how thin or damaged the skin is.

How many Rejuran sessions do I need?

Most plans involve a course of several sessions a few weeks apart, followed by review. The number depends on skin condition and response. A fair plan states the expected number but is reviewed after each visit rather than locked in before the first.

Is needle-free Rejuran cheaper?

Not necessarily. Needle-free assisted delivery uses different consumables and time. It may suit people who want less visible bumping afterwards. Dr Sin Yong will explain whether injection or needle-free delivery fits your skin and timetable, and the quote will reflect the method chosen.

Why do some clinics offer very cheap Rejuran?

Possible reasons include a topical facial rather than an injection, less product, product split between patients or unregistered imports. Ask what exactly is being used, how many syringes, whether it is opened in front of you and who injects it.

Can Rejuran be combined with other treatments?

Often, yes. It is commonly sequenced with laser or energy-based treatments and with hyaluronic acid boosters. Timing matters, so combined plans are set at assessment and each part is listed separately in the written quote. You can then decide which parts to do first.

Is the consultation part of the price?

How consultation is charged is explained before you book. At IN Eternity Clinic the assessment comes first and the written quote follows it, so you know the full cost of any treatment before deciding. See the fees page for how this works.

Related at IN Eternity Clinic
Rejuran at IN Eternity ClinicPDRN explainedNeedle-free skin boosterFees and quotes

Book an assessment

IN Eternity Clinic, 9 Scotts Road, #12-01 Pacific Plaza, Singapore 228210. By appointment with Medical Director Dr Sin Yong. Monday to Saturday, 11am to 8pm. WhatsApp or call +65 8815 3008.

WhatsApp to Enquire →Call +65 8815 3008
S
Dr Sin Yong
MBBS (NUS) · MRCS (Edinburgh) · MSc Aesthetic Medicine (London) · MSc Practical Dermatology (Cardiff)
International KOL — CLASSYS · HIRONIC · DEKA · ALMA · FOTONA · LUTRONIC

References

  1. Squadrito F, Bitto A, Irrera N, et al. Pharmacological activity and clinical use of PDRN. Front Pharmacol 2017;8:224. doi:10.3389/fphar.2017.00224
  2. Park KY, Seok J, Rho NK, et al. Long-chain polynucleotide filler for skin rejuvenation: efficacy and complications in five patients. Dermatol Ther 2016;29(1):37-40. doi:10.1111/dth.12299
  3. Hong JY, Lee YH, Kim H, et al. Therapeutic performance of needle injection versus needle-free jet injector system for polynucleotide filler in skin rejuvenation. J Cosmet Dermatol 2025;24(1):e16595. doi:10.1111/jocd.16595
  4. Singapore Medical Council. Guidelines on Aesthetic Practices for Doctors (2016 edition). healthprofessionals.gov.sg/smc
  5. Health Sciences Authority, Singapore. Infosearch — registered medical devices and health products. hsa.gov.sg

These sources describe mechanisms and general evidence. They are not a promise of any individual result; suitability is decided at an in-person assessment.

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