
Boosters such as Rejuran are often offered for acne scars on their own. Dr Sin Yong at IN Eternity Clinic on Orchard Road explains which scars they can soften, which they cannot, and where they fit in a scar plan.
WhatsApp to Enquire →Key facts ↓Skin boosters help acne scars that are shallow, soft and rolling, and they improve the thin, uneven skin around scars. They do little for deep icepick or sharp-walled boxcar scars, which need TCA CROSS, subcision or fractional resurfacing. Polynucleotides such as Rejuran S, and PDLLA boosters, are usually one part of a layered scar plan, not the whole plan.
Acne scars are not one problem. Severe inflammation in a follicle destroys collagen, and how the skin heals decides the scar’s shape. Icepick scars are narrow, deep tracks that extend into the deep dermis. Boxcar scars are wider with sharp vertical edges. Rolling scars are broad, soft depressions caused by fibrous bands that tether the skin to deeper tissue. Most faces have a mix, which the acne scars page explains in more detail.
A skin booster works in the dermis: it supports repair, hydration and, with some products, new collagen. That helps when the problem is a soft dip in thin skin. It does not cut a fibrous band, lift a deep track or reshape a sharp edge. Matching the tool to the scar type is the most important decision in any scar plan, and the reason boosters on their own often disappoint people with deeper scars.
A practical sign helps. Stretch the skin gently between two fingers: scars that soften or almost disappear are usually rolling or shallow and more likely to benefit from a booster layer; scars that stay sharp and deep when stretched are boxcar or icepick, and need focal or resurfacing treatment. Grading scars this way, under angled light, is part of the first consultation at IN Eternity Clinic.

Shallow rolling scars. Soft, wide depressions that flatten when the skin is stretched respond most readily. After subcision has released the tether, a booster placed under the scar can support the new tissue that forms in the released space.
Uneven texture and thin skin. Years of inflammation, picking and treatment can leave the skin between scars thin and irregular. Polynucleotides such as Rejuran support repair in that skin, and a small randomised study of highly purified polynucleotide in moderate to severe acne scars reported improvement over placebo. PDLLA boosters such as Juvelook prompt gradual collagen change across the cheeks.
Skin that marks easily. In skin that develops pigment after lasers, a course of boosters can be a lower-heat layer within the plan. Boosters do not clear the marks themselves, but they add a step that carries little pigment risk.
“A booster under a scar that is still tied down just spreads around it. Release first, support second, resurface third.”
Icepick scars are too deep and narrow for a booster to fill. They are usually treated with focal TCA CROSS, in which a strong acid is placed precisely into each scar to prompt collagen from the base.
Boxcar scars with sharp edges need resurfacing to soften the walls, such as fractional CO2 with S3 Resurfacing on the DEKA Tetra PRO or RF microneedling. A booster may support healing between sessions but will not change the edge.
Tethered rolling scars need subcision first; a booster placed under a scar that is still tethered tends to spread around it rather than lift it.
Raised scars (hypertrophic or keloid) are a different condition and are not treated with boosters. Red or brown marks after acne are colour rather than depressions; see post-inflammatory pigmentation. Active acne is treated first, as explained on acne treatment, because new inflammation creates new scars.

| Scar type | Booster role | Main treatment |
|---|---|---|
| Shallow rolling | Useful layer | Subcision, then booster or resurfacing |
| Deep rolling | Supportive after release | Subcision |
| Boxcar | Limited | Fractional CO2 or RF microneedling |
| Icepick | Little | TCA CROSS |
| Texture and thin skin | Useful | Booster plus resurfacing |
| Raised (hypertrophic) | None | Scar-specific care |
For a fuller comparison of resurfacing tools, see CO2 vs RF microneedling vs pico for acne scars.
Rejuran S is a thicker polynucleotide gel designed to be placed under individual depressed scars, a few at a time. Rejuran Healer is spread across the face for the skin between scars. The two are often combined; Rejuran Healer vs HB vs S vs Eye explains the differences.
PDLLA boosters prompt collagen and suit shallow scars and texture over a wider area, with the caveat that they cannot be dissolved. Hyaluronic acid boosters hydrate and can make the skin look smoother for a while, but they do little for the scar itself. Small hyaluronic acid fillers are occasionally placed under a single soft scar for an immediate lift, accepting that the effect is temporary.
Topical exosome products may be applied after laser or microneedling to support recovery; they are not injected. Exosome skin boosters explained covers what is and is not known.
At IN Eternity Clinic, scar treatment starts with mapping each area under angled light, grading the scars and noting skin type. Active acne is controlled first. Tethered scars are then released with subcision; a booster may be placed in the same area at that visit or a few weeks later to support the new tissue. Resurfacing follows in a course, with boosters between sessions where the skin is thin or slow to recover. Combined approaches like this are described on 4D Scar Reconstruction and acne scar treatment.
Scar change is measured in months, not weeks. Expect several sessions over six months or more for moderate scarring, and improvement rather than erasure. Bruising and small bumps settle within days after boosters; resurfacing has its own recovery. In darker skin, settings and intervals are chosen to limit pigment risk. If you are comparing quotes, acne scar treatment cost explains what drives the total.
Numbing cream is applied for around 30 to 45 minutes. Rejuran S is placed with a fine needle under each scar, which feels like a series of small pricks and pressure; Rejuran Healer across the cheeks feels similar but covers a wider area. PDLLA is often placed through a few cannula entry points. Sessions take about an hour including numbing.
Expect small raised bumps, mild swelling and occasional pinpoint bruises, which usually settle within a day or two for bumps and up to a week for bruises. Most people return to work the next day. If subcision is done at the same visit, bruising is more likely and can last a week or more; this is planned around your diary. Avoid picking at healing skin, use sunscreen daily, and keep active acne under control, because new inflammation undoes the work.
Progress in scar treatment is easier to see in photographs than in the mirror, because change is gradual and you see your skin every day. Standardised photographs under the same angled light are taken at the start and at review, so you and Dr Sin Yong can judge what each step has added.
They help some scars. Shallow, soft rolling scars and thin, uneven skin between scars often improve, especially when a booster follows subcision. Deep icepick scars, sharp-walled boxcar scars and raised scars respond little to boosters and need other treatments. Most people need a combined plan, and boosters are one part of it.
Rejuran S, a thicker polynucleotide gel, is designed to be placed under individual depressed scars, and Rejuran Healer supports the surrounding skin. A small randomised study of polynucleotide in acne scars reported improvement over placebo. It suits shallow scars, and works as a layer alongside subcision and resurfacing rather than as a stand-alone treatment.
They do different jobs. Fractional laser and RF microneedling resurface the scar and stimulate collagen, which suits boxcar scars and texture. Boosters support the dermis without heat, which suits thin skin and shallow rolling scars. Many plans use both, spaced apart, with subcision for tethered scars.
A typical booster course is around three sessions a few weeks apart, but in a scar plan the number depends on how boosters are combined with subcision and resurfacing. Expect the whole plan to run over several months. Progress is reviewed against photographs taken in standard angled light at each stage.
Yes. Boosters do not heat the skin, so the risk of post-inflammatory pigmentation from the booster itself is low, which makes them a useful layer in darker skin. Bruising and small bumps can occur. Lasers in the same plan are set more conservatively and spaced further apart.
Cost depends on the booster used, how many syringes the scarred areas need, the number of sessions and whether subcision or resurfacing is part of the plan. Dr Sin Yong gives a written, itemised quote after mapping your scars. The consultation fee is waived with any medical treatment.
IN Eternity Clinic, 9 Scotts Road, #12-01 Pacific Plaza, Singapore 228210. By appointment with Medical Director Dr Sin Yong. Monday to Saturday, 11am to 8pm. WhatsApp or call +65 8815 3008.
These sources describe mechanisms and general evidence. They are not a promise of any individual result; suitability is decided at an in-person assessment.