
Some treatments are popular online but do not meet the clinic’s standard for registration, evidence or reversibility. Medical Director Dr Sin Yong explains what IN Eternity Clinic declines, and why.
WhatsApp to Enquire →Key facts ↓IN Eternity Clinic does not offer injectables that are not registered with Singapore’s Health Sciences Authority (HSA) for their use, injectable exosome preparations, unregistered fat-dissolving injections, animal-collagen fillers such as Deusaderm, or non-absorbable fillers. The reasons are regulatory status, limited evidence on safety and dosing, or complications that are hard to reverse.
Patients often ask about treatments they have seen online or been offered elsewhere. A clear answer saves time and, sometimes, harm. Declining a treatment here is not a judgement on anyone who has had it; it reflects the standard IN Eternity Clinic applies to everything it uses: the product must be registered for its use in Singapore, there must be reasonable published evidence on safety and dosing, and the clinic must be able to manage the complications it can cause.
This list is reviewed as products are registered and evidence changes. New treatments under consideration sit on the new treatments watchlist until they meet that standard.

In Singapore, medicines and medical devices — including fillers, skin boosters and botulinum toxin — are regulated by HSA. Products bought online, brought in from overseas without registration, or sold as do-it-yourself injection kits have not been assessed for quality or labelling here, and their contents cannot be verified in the clinic. HSA has warned the public against self-injecting such products.
IN Eternity Clinic uses only registered products obtained through authorised suppliers, and records batch numbers. How this works is explained on HSA registration explained and product sourcing.
“If I cannot tell you what is in the vial, where it was made and that it is registered for that use, I will not inject it.”
Exosomes are tiny vesicles released by cells that carry proteins and genetic signals. Laboratory work on their role in repair is genuine and interesting. The products sold to aesthetic clinics, however, come from many sources — human cell cultures, plants or animals — with little standardisation of what each vial contains, and many are sold as cosmetics intended for the skin surface rather than for injection.
Controlled human evidence on injecting these preparations, including safe dosing and long-term effects, remains limited. Until a product is registered for injection and the evidence is clearer, IN Eternity Clinic does not inject exosome preparations into the skin or scalp. For skin quality and hair, registered alternatives with longer track records are used instead.

Injectable fat dissolving relies on substances that break down fat cell membranes; deoxycholic acid is the agent most studied. Mixed “lipolysis” cocktails, and products not registered with HSA for that use, vary in strength and content, and can cause marked swelling, nodules, skin injury and, near the jaw, temporary nerve weakness.
IN Eternity Clinic does not use them. For fat under the chin and on the body, device-based options are offered and assessed case by case, such as Onda Pro, the 4K Body Lift and double chin treatment.
Animal-collagen fillers. Injectables made from purified animal collagen, such as the porcine-collagen product Deusaderm, are not used at IN Eternity Clinic. Its injectables are limited to hyaluronic acid fillers and absorbable collagen stimulators that it uses routinely and knows how to monitor and manage.
Non-absorbable fillers. Liquid silicone and other fillers that the body cannot break down are not used, because late lumps, migration and inflammation can appear years later and are difficult to remove.
Social-media trends. Needle-free “hyaluron pens”, at-home injection kits and similar trends are declined on safety grounds. Interest alone is not a reason to adopt a treatment.
Ask what the product is called, who makes it, whether it is registered with HSA for that use, and who will perform the treatment. Ask how complications are handled and whether the product can be reversed. A clinic should answer these plainly. For more, read how to check an aesthetic clinic’s licence and aesthetic clinic red flags.
Deusaderm is an injectable made from purified porcine (pig) collagen. IN Eternity Clinic does not use it or any animal-collagen filler, so Dr Sin Yong cannot comment on it from his own practice. If you are considering it, ask whether the product is registered with HSA for that use, whether your allergy history has been reviewed, and how complications would be managed.
Exosome products vary widely in source and content, and many are sold as cosmetics for the skin surface. Evidence from controlled human studies on injecting them is still limited, particularly on dosing and long-term effects. IN Eternity Clinic does not inject exosome preparations while registration and evidence remain unclear.
Products not registered with HSA, and mixed lipolysis cocktails, vary in strength and content and can cause significant swelling, lumps and nerve weakness near the jaw. IN Eternity Clinic does not use them. Device-based options are assessed instead, depending on whether the fullness is fat, loose skin or jaw structure.
HSA maintains online registers for health products, including therapeutic products and medical devices, which can be searched by product name. You can also ask the clinic to show you the product packaging and batch details before treatment. A reputable clinic should be comfortable doing this.
Possibly, if a product becomes registered for its use and good evidence on safety and dosing is published. New options are tracked on the clinic’s watchlist and reviewed by Dr Sin Yong. The decision rests on registration, evidence and whether complications can be managed, not on popularity.
Registered hyaluronic acid fillers and skin boosters, absorbable collagen stimulators, prescription anti-wrinkle injections, and energy-based treatments for lifting, fat reduction and skin quality. Dr Sin Yong will explain at consultation which registered option, if any, suits what you were hoping to achieve.
IN Eternity Clinic, 9 Scotts Road, #12-01 Pacific Plaza, Singapore 228210. By appointment with Medical Director Dr Sin Yong. Monday to Saturday, 11am to 8pm. WhatsApp or call +65 8815 3008.
These sources describe mechanisms and general evidence. They are not a promise of any individual result; suitability is decided at an in-person assessment.